Best Alternatives to Microsoft 365 Agents SDK

ACI.dev

Agent Frameworks· aci.dev

Freemium

Open-source tool-calling and unified MCP platform that connects agents to hundreds of app actions.

AG-UI

Agent Frameworks· docs.ag-ui.com

Open source

Open agent-user interaction protocol for connecting AI agents to frontend applications with shared event and state primitives.

Agent2Agent Protocol JS SDK

Agent Frameworks· a2a-protocol.org

Open source

Official JavaScript SDK for the Agent2Agent protocol, useful when builders need interoperable agent-to-agent communication in apps.

AgentDock

Agent Frameworks· agentdock.ai

Open source

Open-source framework and runtime for building AI agents with tools, templates, and deployable agent workflows.

AgentScope

Agent Frameworks· agentscope.io

Open source

Agent framework for building and running observable, understandable, and controllable agent systems.

Apify MCP Server

Agent Frameworks· apify.com

Open source

Official Apify MCP server that lets AI agents discover and run Apify Actors as tools for web automation, scraping, and data extraction workflows.

BeeAI

Agent Frameworks· beeai.dev

Open source

BeeAI AgentStack is open infrastructure for building, deploying, and sharing AI agents without vendor lock-in, with docs and source code for agent runtime workflows.

CAMEL-AI

Agent Frameworks· camel-ai.org

Open source

Open-source multi-agent framework for building, simulating, and coordinating autonomous AI agent societies and workflows.

Cloudflare Agents SDK

Agent Frameworks· developers.cloudflare.com

Freemium

TypeScript SDK and runtime primitives for building AI agents on Cloudflare Workers, Durable Objects, and Workflows.

Dify

Agent Frameworks· dify.ai

Freemium

Open-source platform for building agentic workflows, RAG apps, and LLM application backends.

FastAPI-MCP

Agent Frameworks· fastapi-mcp.tadata.com

Open source

MCP adapter that exposes FastAPI endpoints as authenticated Model Context Protocol tools.

Flowise

Agent Frameworks· flowiseai.com

Open source

Open-source low-code platform for building LLM apps, agent flows, RAG pipelines, and production chat automations.

IBM MCP Context Forge

Agent Frameworks· ibm.github.io

Open source

MCP, A2A, and API gateway for centralized tool discovery, guardrails, and agent integrations.

Klavis AI

Agent Frameworks· klavis.ai

Freemium

MCP integration platform and gateway for connecting AI agents to authenticated third-party tools through hosted and open-source MCP servers.

Langbase

Agent Frameworks· langbase.com

Freemium

Serverless AI developer platform for building, collaborating on, and deploying AI agents and features.

Langflow

Agent Frameworks· langflow.org

Open source

Visual Python framework for building and deploying agentic and RAG applications with reusable components and API endpoints.

Langroid

Agent Frameworks· langroid.github.io

Open source

Multi-agent LLM framework for building tool-using, retrieval-aware, and conversational applications in Python.

MCP Gateway & Registry

Agent Frameworks· agentic-community.github.io

Open source

Open-source gateway and registry for governing MCP servers, OAuth access, discovery, and auditable agent tool use.

MCP Inspector

Agent Frameworks· github.com

Open source

Official visual testing and debugging tool for Model Context Protocol servers.

mcp-agent

Agent Frameworks· docs.mcp-agent.com

Open source

Composable Python framework from LastMile AI for building agents around Model Context Protocol servers and simple workflow patterns.

Microsoft Agent Framework

Agent Frameworks· learn.microsoft.com

Open source

Open Microsoft framework for building, orchestrating, and deploying production AI agents and multi-agent workflows across Python and .NET with MCP/A2A support.

Microsoft AutoGen

Agent Frameworks· microsoft.github.io

Open source

Open-source Microsoft framework for building, orchestrating, and evaluating multi-agent AI applications.

Microsoft Semantic Kernel

Agent Frameworks· learn.microsoft.com

Open source

Microsoft agent orchestration SDK for composing tools, planners, memory, and enterprise-grade LLM workflows across app stacks.

n8n

Agent Frameworks· n8n.io

Freemium

Source-available workflow automation platform for building AI agent workflows, tool integrations, and production automations across APIs and apps.

Serena

Agent Frameworks· github.com

Open source

MCP toolkit that gives coding agents semantic code retrieval, symbol understanding, and repository editing capabilities.

smolagents

Agent Frameworks· huggingface.co

Open source

Hugging Face agent library for compact code-oriented agents, tool use, and model-driven workflows.

Strands Agents

Agent Frameworks· strandsagents.com

Open source

Open-source Python and TypeScript SDK for building production AI agents across local, model-provider, and cloud deployment paths.

Supabase MCP Server

Agent Frameworks· supabase.com

Open source

Official Supabase MCP server that lets AI tools inspect and operate Supabase projects through the Model Context Protocol.

Supergateway

Agent Frameworks· github.com

Open source

Open-source gateway that exposes stdio-based MCP servers over SSE or WebSocket for remote agent clients and debugging.

Timbal

Agent Frameworks· timbal.ai

Open source

Open-source Python framework and developer platform for composing AI agents and explicit workflows with async functions, Pydantic validation, streaming, tracing, and MCP support.

ToolHive

Agent Frameworks· docs.stacklok.com

Open source

Enterprise-grade runtime for running and managing MCP servers for agent tool access.

VoltAgent

Agent Frameworks· voltagent.dev

Open source

Open-source TypeScript agent framework and engineering platform for building, orchestrating, and observing AI agents.